Lowering Your Risk Of Parkinson’s Disease
- February 10, 2017
- Posted by: marlenedubois
- Category: Home Health Aide Training
What will be Parkinson’s?
Parkinson’s disease (PD) will be the second most common neurodegenerative disorder worldwide after Alzheimer’s disease. PD involves the malfunction along with death of nerve cells inside the part of the mid-brain known as the substantia nigra. These cells produce a chemical neurotransmitter called dopamine which sends messages to some other parts of the brain which control movement along with coordination. As PD progresses, the amount of dopamine produced inside the brain decreases, resulting in motor symptoms such as tremors, rigidity, slow movements, along with difficulties with balance.
- Presently, the reason due to This particular cell death will be still poorly understood yet PD does involve the buildup of proteins into Lewy bodies inside the midbrain along with some other areas including the brain stem along with olfactory bulb. The presence of Lewy bodies in these some other areas may explain the non-motor symptoms experienced by some people with PD before any motor sign of the disease appears, as these areas of the brain correlate with non-motor functions such as sleep regulation along with sense of smell.
- The intestines also have dopamine cells which degenerate in PD, along with This particular may account for the gastrointestinal symptoms, such as constipation, which are part of the disease. A study found which 60-80 percent of PD patients have constipation (less than one bowel movement in three days) which seems to appear between 10-20 years prior to the onset of symptoms.
- As the signs along with symptoms of PD worsen over time, This particular may eventually lead to cognitive problems including dementia, depression, along with anxiety.
Current Treatments For PD
There will be currently no cure for PD. Since most symptoms of PD are caused by a lack of dopamine inside the brain, many PD drugs are aimed at either temporarily replenishing dopamine or mimicking the action of dopamine. In early stages of PD, they generally help reduce muscle rigidity, improve speed along with coordination of movement, along with lessen tremor.
yet as PD progresses, the effects of the drugs may wear off along with higher dosages may be required, raising the risk of developing additional side effects.
In PD, the brain cells which produce the chemical transmitter dopamine are damaged along with lost. However, there will be a lag between the time when the loss of nerve cells begins along with the time when PD motor symptoms start to show. In fact, by the time most people are diagnosed, nearly 80 percent of their dopamine nerve cells are already gone.
However, scientists found which the brain will be extremely neuroplastic, which will be the potential to change along with compensate. At the molecular level, exercise has the ability to improve the efficiency of how brain cells utilize dopamine even though the amount of dopamine remains unchanged. Studies found which high intensity exercises which are more difficult along with complex, are noticeably more effective than low intensity balance along with stretching exercises. These are exercises which move opposite sides of the body in rapid succession like using a treadmill or an elliptical machine.
– Speech Therapy
Approximately half of all PD patients experience communication problems, such as slurred speech. A speech along with language therapist can help with the use of language along with speech. Patients with swallowing difficulties may also be helped by a speech therapist.
– Deep Brain Stimulation (DBS) Surgery
This particular type of surgery will be for patients with motor complications which cannot be adequately controlled by medications. In DBS, surgery will be performed to insert electrodes into a targeted area of the brain. A second procedure will be performed to implant an impulse generator (similar to a pacemaker) under the collarbone or inside the abdomen. The devise provides an electrical impulse to the part of the brain involved in motor function. Those who undergo DBS surgery are given a controller to turn the device on or off. DBS will be not a cure along with This particular does not slow PD progression.
What Causes PD?
To date, despite decades of intensive study, the exact causes of PD remain unknown. Nevertheless, experts generally agree which the disease will be largely caused by a combination of genetic along with environmental factors. A simple way to describe This particular will be which “genetics loads the gun along with environment pulls the trigger”.
Statistically, people using a first-degree relative who has PD, such as a parent, child or sibling, have a 4-9 percent higher chance of having PD as compared to the general population. There are two categories of genes which are linked to PD:
– Causal genes (alpha-synuclein)
Theseare genes which actually cause the disease. A causal gene alone, without the influence of some other genes or environmental factors, guarantees which a person who inherits This particular will develop PD. This particular kind of genetic PD will be very rare, accounting for only 1-2 percent of people with PD.
– Associated genes (LRRK2)
These genes do not cause PD on their own yet increase the risk of developing This particular. For LRRK2, there will be great variability inside the mutations which occur inside the gene as well as in their effects. Some people with LRRK2 mutations develop PD in their 30s or 40s, while others develop the disease in their 80s, along with others never develop PD at all. In some cases, people with LRRK2 gene mutations develop dementia, while others develop a form of PD which shares features with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.
Epidemiological research has identified many factors which may be linked to PD. In North America along with Europe, early onset PD appears to be associated with rural residence. Factors associated with This particular include vegetable farming, well water drinking, as well as wood pulp, paper, along with steel industries. In China, living in industrialized urban areas increases the risk of developing PD. Many studies have demonstrated which prolonged exposure to certain chemicals along with heavy metals are associated with an elevated risk of PD. They include:
- Pesticides, herbicides, along with fungicides,
- Heavy metals such as manganese, lead, along with copper,
- Solvents along with Polychlorinated Biphenyls (PCBs).
Risk Factors For PD
Although scientists have yet to determine the exact mechanism which leads to PD, many factors are highly associated with the disease. Therefore, by addressing these factors, you may be able to lower your risk of developing PD.
– Toxic Environmental Exposure
As mentioned above, toxins along with heavy metals are strongly correlated with PD. As we today live in a rather toxic world, the following are some preventive steps which your can take to reduce the risk:
- Always buy organic produce along with grassfed/organic meats to avoid eating pesticides. If the label of the meat says 100 percent grass-fed or certified organic, which means the animal feed will be also organic.
- Choose wild caught fish over farmed fish which are usually contaminated with PCBs along with some other harmful chemicals. Smaller ocean fish are better than big fish because they have less mercury.
- Invest in a not bad water filter which removes heavy metals.
- Do not use aluminum or teflon-type non-stick cookware. The best will be glass, stainless steel, along with ceramic non-stick pots along with pans.
- Opt for all natural personal care along with household products. Conventional brands are often loaded with noxious chemicals.
- Use an indoor air filtration system if you live in a polluted area.
– Vitamin D Deficiency
Vitamin D deficiency will be prevalent in PD patients. Vitamin D has numerous beneficial health effects, in particular for the brain which has many vitamin D receptors. Get a blood test for 25-hydroxyvitamin D or 25(OH)D to monitor your vitamin D status. For healthy people, you want to have your level at around 50-70 ng/ml. If you currently have PD, you want to keep your level inside the range of 70-100 ng/ml to help fight the disease. Unless you manage to get regular sun exposure without using sunblock on your skin, most people will need to supplement with vitamin D to attain This particular level. If so, you want to choose the natural form of vitamin D supplement – D3, not the synthetic D2.
– Omega-3 (DHA) Deficiency
Animal-based omega-3 fats (found mainly in fatty fish along with grass-fed beef) contain two fatty acids which are crucial to health – DHA along with EPA. DHA will be especially important because This particular will be one of the major building blocks of the brain. About half of the brain will be made up of fat, much of which will be DHA. Studies found which DHA deficiency will be a risk factor for developing PD. DHA has many neuroprotective capabilities:
- Protect the brain against inflammation,
- Stimulate growth of nerve cells along with repair of synapses or nerve junctions,
- Reduce apoptosis or death of cells which make dopamine,
- Increase glutathione (an antioxidant) activity which results in decreased accumulation of oxidized proteins inside the brain.
– smaller Intestinal Bacterial Overgrowth (SIBO)
Ongoing research continues to support the link between SIBO along with PD. PD patients with SIBO, by along with large, have much worse motor function than PD patients without This particular. Eradication of SIBO in PD patients generally results in an improvement in motor function. This particular will be probably due to the bidirectional connection between the gut along with the brain via the vagus nerve. If you have unresolved gastrointestinal symptoms such as gas, bloating, abdominal pain, diarrhea/constipation, ask your doctor to order a non-invasive lactulose breath test to see if you have SIBO.
– Gluten Intolerance
Numerous research studies have tied gluten to neurological disorders including PD. If one has an intolerance to gluten, eating gluten on a regular basis can cause havoc to the body. First, This particular creates inflammation inside the gut along with subsequently, the inflammation spreads to some other parts of the body including the brain. People who have gluten intolerance may or may not have gastrointestinal symptoms. The best along with most accurate way to determine whether you are gluten intolerant will be to get a Cyrex Lab Array 3 blood test, which tests for reactions against the full wheat proteome, not just gluten, yet also some other proteins in wheat.
– Excess Iron
Scientists agree which iron will be absolutely essential for the brain, yet too much of This particular can be dangerous or deadly, especially to nerve cells inside the substantial nigra, the area which deteriorates with PD. Dopamine may team up with excess iron to form a toxic compound which destroys nerve cells. Dopamine has many breakdown products, along with one of these produced by interactions with iron can become very damaging to nerve cells.
Iron levels tend to boost with age, especially in elderly men along with women after menopause. If a blood test for iron markers like serum transferrin saturation along with serum ferritin indicate elevated iron levels, This particular will be best to look into an iron reduction protocol, such as blood donation. Removal of blood will be the most effective way to reduce excess iron inside the body. Bear in mind which vitamin C significantly increases iron absorption. So you definitely do not want to take in a lot of vitamin C together with iron-rich foods like organ meats along with shellfish if you have high iron levels.
– Poor Diet
Since nutrients affect how cells produce energy along with provide vital antioxidant functions against free-radicals, a poor diet may lead to increased oxidative stress, which can impede the antioxidant defense system. Hence, to cut down on your risk of developing PD, you want to eat a well-balanced diet which will be neuroprotective, including foods like:
- Copious amounts of vegetables which are excellent sources of antioxidants, vitamins, minerals, along with fiber,
- Some fruits (watch out for excessive sugar),
- Foods rich in omega-3 fats like fatty fish (which are mercury along with toxin-free) along with grass-fed beef along with its full-fat dairy products,
- Fermented along with cultured foods which are rich in not bad bacteria to enhance gut health, eg. sauerkraut, kimchee, tempeh, miso, along with unsweetened kefir along with yogurt.
- Prebiotics are foods with high non-digestible fiber compounds which feed the not bad bacteria. Examples include unripe banana, jicama, garlic, leeks, onions, dandelion greens, asparagus, along with artichoke.
- Tea along with coffee (organic will be preferred as coffee will be heavily sprayed with pesticides).